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ethylene glycol monobutyl ether health effects

Miller RR, Hermann EA, Young JT, Landry TD, Calhoun LL. 2-Butoxyethanol (bu-tox-zi-eth-an-ol) has many names, including ethylene glycol monobutyl ether, ethylene glycol butyl ether, ethylene glycol n-butyl ether, Butyl Cellosolve, butyl glycol, butyl Oxitol, glycol butyl ether… Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, ... 2 Japan Industrial Safety and Health Association. -, Toxicol Appl Pharmacol.  |  Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, isopropyl acetate and propyleneimine, and classifications on carcinogenicity, occupational sensitizer and reproductive toxicant ... 2 Japan Industrial Safety and Health Association. Substance Name — Ethylene glycol monobutyl ether (EGBE) CASRN — 111-76-2 Last Revised — 3/31/2010 . It is concluded that the available information continues to support the current ACGIH TWA8-TLV of 25 ppm with a STEL of 75 ppm. 4.3. 2-Butoxyethanol acetate is a colorless liquid with a fruity odor. REACH regulation aims to improve the protection of human health and the environment from the risks that can be ... new labelling, classification or hazard statement, neither reflect other factors that affect the susceptibility of the effects ... 2-butoxyethanol ethylene glycol monobutyl ether butyl cellosolve . 4 Fukushima Medical University. No harmful effects were seen on their lungs or hearts. The RfD is an estimate (with uncertainty … Vapors irritate eyes and nose. 1984 Aug;57:47-68. doi: 10.1289/ehp.845747. FIRST AID MEASURES First aid measures Eye contact Rinse … This chemical inventory is OSHA's premier one-stop shop for occupational chemical information. J Occup Health. Epub 2017 Jun 26. 4 Fukushima Medical University. It compiles information from several government agencies and organizations. Gaschromatographic determination of butoxyacetic acid after hydrolysis of conjugated metabolites in urine from workers exposed to 2-butoxyethanol. Respiratory Effects: Inhaled ethylene glycol can irritate the respiratory tract. GENERIC NAME(S): Carbitol (Bulk) ... You may report side effects to Health Canada at 1-866-234-2345. Symptoms may include tiredness, … Ethylene Glycol Monobutyl Ether 111-76-2 <25 * *The exact percentage (concentration) of composition has been withheld as a trade secret. The MRL is an estimate of the daily human exposure to a hazardous substance that is likely to be without appreciable risk of adverse, non-cancer health effects over a specified duration of exposure. Br J Ind Med.  |  DEG is a widely used solvent. In humans, 100 ppm (69 mg/kg bw/day) resulted in ocular and respiratory Irritation, altered taste and nausea (Carpenter et al., 1956). Inhalation: Toxic ifinhaled. Skin Contact Rinse with clear water Stability No data submitted 3.2. In both the ethylene and diethylene glycol series, the relative rate of absorption declined from methyl to ethyl to butyl ether derivatives. The acute and subehronic toxicity of EGEE, EGPE and EGBE was reviewed by C. C. Conaway (Texaco, GENERIC NAME(S): Carbitol (Bulk) ... You may report side effects to Health Canada at 1-866-234-2345. 111-76-2], considering butoxyacetic acid in urine to characterise the internal exposure. 2-Butoxyethanol is an organic compound with the chemical formula BuOC 2 H 4 OH (Bu = CH 3 CH 2 CH 2 CH 2).This colorless liquid has a sweet, ether-like odor, as it derives from the family of glycol ethers, and is a butyl ether of ethylene glycol… 185-191, 1984 Acute and Subchronic Toxicity of Ethylene Glycol Monobutyl Ether by Tipton R. Tyler* The available information on the acute and subchronic toxicity of ethylene glycol monobutyl ether is reviewed. Epub 2017 Jun 26. -, Sangyo Igaku. The available information on the acute and subchronic toxicity of ethylene glycol monobutyl ether is reviewed. Effects observed in humans included nasal and … 1987 Nov;91(2):222-34. US NIOSH Target Organs & Routes of Entry Bauer P, Weber M, Mur JM, Protois JC, Bollaert PE, Condi A, Larcan A, Lambert H. Intensive Care Med. ICSC Routes of Exposure and Symptoms. DIETHYLEN Glycol M-ETHYL ETHER Liquid. 2-Butoxyethanol (ethylene glycol monobutyl ether): Target Organs and Levels of Evidence for TR-484 Toxicology and Carcinogenesis Studies of 2-Butoxyethanol (CASRN 111-76-2) in F344/N Rats and B6C3F1 Mice (Inhalation Studies) DIPROPYLENE GLYCOL BUTYL ETHER . Fast, free, expert help 24×7×365 1‑800‑222‑1222. EPA/635/R-08/006F. Acute (short-term) exposure of humans to ethylene glycol by ingesting large quantities causes three stages of health effects… Pubmed Abstract It has many names including ethylene glycol monobutyl ether, ethylene glycol butyl ether, ethylene glycol n-butyl ether, Butyl Cellusolve, butyl glycol, and butyl Oxitol. 3 Independent Consultant. In the first study, a group of two men and six rats were exposed simultaneously for 4 hours to an EGBE concentration of 113 ppm in a 1,250 cubic ft room. Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, isopropyl acetate … 11.1. 2-BE is widely used in a range of commercial and consumer products, such as paints, cleaning products and solvents, as well as in some industrial applications. 1. On the other hand, ethylene glycol, ethylene glycol monopropyl ether, ethylene glycol monobutyl ether, ethylene glycol monophenyl ether, ethylene glycol monoacetate or ethylene glycol diacetate showed no such an effect. Read More. Toxicological Review of Ethylene Glycol Monobutyl Ether (EGBE) (CAS No. Health Hazard Assessments for Noncarcinogenic Effects . Note: Javascript is disabled or is not supported by your browser. This database provides human health benchmarks for pesticides that may be present in drinking water. It is a colorless, practically odorless, poisonous, and hygroscopic liquid with a sweetish taste. Transient non-cardiogenic pulmonary edema following massive ingestion of ethylene glycol butyl ether. The substance can be absorbed into the body by inhalation, through the skin and by ingestion. It is used as a solvent for lacquers, varnishes, enamels, and epoxy resins. Toxicol Lett. NIOSH Pocket Guide to Chemical Hazards - Centers for Disease Control and Prevention (CDC) ... compared to other product formulations. Effects of short-term exposure The substance is irritating to the eyes, skin and respiratory tract. Nausea and … ETHYLENE GLYCOL N-BUTYL ETHER may react with bases, aluminum and oxidizing materials. Final report on the safety assessment of Triethylene Glycol and PEG-4. Diethylene Glycol Poisoning This can cause anemia. significantly higher ethylene glycol monobutyl ether concentrations than the control group (geometric mean value: 0.14vs. ETHYLENE GLYCOL ETHERS PANEL TO REMOVE ETHYLENE GLYCOL MONOBUTYL ETHER FROM THE TOXICS RELEASE INVENTORY UNDER SECTION 313 OF THE EMERGENCY PLANNING AND COMMUNITY RIGHT-TO-KNOW ACT OF 1986 Jonathon Busch Director, Ethylene Glycol … METHODS 53 Impregnation workers from two factories that make copper clad laminate with EGME as a solvent were recruited as the exposed group. ethylene glycol was prepared by the Institute of Terrestrial Ecology, United Kingdom, based on the report Environmental hazard assessment: Ethylene glycol (Nielsen et al., 1993). The main systemic adverse effects of 2-butoxyethanol are on the haematopoietic system (haemolytic effects), followed by possible teratogenic and testicular effects. For more information about this message, please visit this page: Agency for Toxic Substances & Disease Registry, 2-Butoxyethanol and 2-Butoxyethanol Acetate, Health Effects of Exposure to Substances and Carcinogens, Community Environmental Health Education Presentations, Case Studies in Environmental Medicine (CSEM), Toxicology Curriculum for Communities Trainer's Manual, Compendium of Papers on MRLs and Health Effects, Agency for Toxic Substances and Disease Registry. Substance name : Glycol Ether EB CAS-No. This site needs JavaScript to work properly. In this document, NIOSH recommends occupational exposure limits for ethylene glycol monobutyl ether (EGBE) and its acetate, ethylene glycol monobutyl ether acetate (EGBEA). The substance may cause effects on the central nervous system, blood, kidneys and liver. some . This assessment summarizes available information on Toxicol Appl Pharmacol. Reference Dose (RfD) for Chronic Oral Exposure . It is also used in some ink and spot remover compounds. Diethylene glycol (DEG) is an organic compound with the formula (HOCH 2 CH 2) 2 O. It is a colorless, practically odorless, poisonous, and hygroscopic liquid with a sweetish taste. It is miscible in water, alcohol, ether, acetone, and ethylene glycol… 1988 Oct;43(1-3):5-21. doi: 10.1016/0378-4274(88)90017-3. DIETHYLEN Glycol M-ETHYL ETHER Liquid. EPA has denied a petition to remove Ethylene Glycol Monobutyl Ether ... toxicity data for EGBE and concluded that it can reasonably be anticipated to cause serious or irreversible chronic health effects in humans, specifically, liver toxicity and concerns for hematological effects. O-butyl ethylene glycol butyl glycol EGBE ethylene glycol n-butyl ether glycol butyl ether monobutyl glycol ether 3-oxa-1-hepatanol Chemical name (CAS) 2-butoxyethanol CAS number 111-76-2 Since the MAK documentation from 1983 and 1986 (“2-Butoxyethanol”, Volume 6, Flammable and/or toxic … Find Lowest Prices. ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE is incompatible with the following: Oxidizers (NIOSH, 2016). Ethylene Glycol Monobutyl Ether; Community Right-To-Know Toxic Chemical Release Reporting, 60818-60825 [2015-25674] CAS-Number. Occupational Exposure to Ethylene Glycol Monobutyl Ether and Ethylene Glycol Monobutyl Ether Acetate. NLM some . 2-Butoxyethanol was classified in Symptoms/effects after skin contact : Harmful in contact with skin. Environmental Health Perspectives Vol. 3 Independent Consultant. Effects of short-term exposure The substance is irritating to the eyes, skin and respiratory tract. FIRST AID MEASURES First aid measures Eye contact Rinse thoroughly with plenty of water for at least 15 minutes, lifting lower and upper eyelids. Ethylene glycol monobutyl ether has also been tested for teratogenldty … Information on toxicological effects . NIOSH Criteria for a Recommended Standard. Abbreviations for 2-butoxyethanol include EGBE and BE [1]. U.S. Department of Health and Human Services, Public Health Service, National Institutes of Health… 2-Butoxyethanol is an organic compound with the chemical formula BuOC 2 H 4 OH (Bu = CH 3 CH 2 CH 2 CH 2).This colorless liquid has a sweet, ether-like odor, as it derives from the family of glycol ethers, and is a butyl ether of ethylene glycol.As a relatively nonvolatile, inexpensive solvent, it is used in many domestic and industrial products because of its properties as a surfactant. Cincinnati, OH, US Department of Health and Human Services, National Institute for Occupational Safety and Health, Division of Standards Development and Technology Transfer, 1990. Exposure to 60 ppm aerosolized ethylene glycol caused very noticeable irritation. 2-Butoxyethanol (bu-tox-zi-eth-an-ol) has many names, including ethylene glycol monobutyl ether, ethylene glycol butyl ether, ethylene glycol n-butyl ether, Butyl Cellosolve, butyl glycol, ... if they do, what the type and severity of these health effects … Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. Another group of 121 lamination workers with indirect exposure to EGME was recruited as the control group. Summary: 2-Butoxyethanol is a clear colorless liquid that smells like ether. Read More. Office of Pesticide Programs Pesticide Chemical Search. NIOSH Pocket Guide to ... in this product - not the product itself - compared to other product formulations. 1983 May;68(3):405-14 NIOSH IDLH: The National Institute for Occupational Safety and Health Immediately Dangerous to Life or Health Ethylene Glycol Monobutyl Ether (Laboratory) Revision Date 15-Dec-2015 Engineering …  |  ICSC Long-Term Exposure. 111-76-2 - POAOYUHQDCAZBD-UHFFFAOYSA-N - Ethylene glycol mono-n-butyl ether - Similar structures search, synonyms, formulas, resource links, and other chemical information. The ratings reflect potential health … 1979 Jan;21(1):29-35 It is an ether-ester derivative. Ethylene Glycol Monobutyl Ether 111-76-2 <25 * *The exact percentage (concentration) of composition has been withheld as a trade secret. Precautions. Ethylene … NIH Where is it found and how is it used? Occupational exposure limits for ethylene glycol monobutyl ether, isoprene, isopropyl acetate and propyleneimine, and classifications on carcinogenicity, occupational sensitizer and reproductive toxicant. Data from animal studies have been examined from the standpoint of dose-response relationships and the sensitivity of various animal species, including man, to the effects of this chemical. Effect of age on the toxicity and metabolism of ethylene glycol monobutyl ether (2-butoxyethanol) in rats. It attacks some forms of plastics, rubber and coatings. Archives of Toxicology, 82(2), 125-136. This substance ranges from B to C depending on concentration/usage. I. Health Effects Division (7509C) Pauline Wagner, Chief Inert Ingredient Assessment Branch (IIAB) Registration Division (7505C) BACKGROUND Attached is the science assessment for one exemption from the requirement of a tolerance for ethylene glycol monobutyl ether (EGBE). In evaluating the hazard that this chemical … Print Share on: Evidence. Acute toxicity: Oral: Harmful if swallowed. 1992;18(4):250-1. doi: 10.1007/BF01709843. by Alicia Minns, MD. ETHYLENE GLYCOL MONOBUTYL ETHER ACETATE For Synthesis Safety Data Sheet www.lobachemie.com 03/06/2016 3/8 4.2. Chemical Name. 4. 2-Butoxyethanol is a clear colorless liquid that smells like ether. Would you like email updates of new search results? ICSC Short-Term Exposure. Aspects of biological monitoring of exposure to glycol ethers. 2-Butoxyethanol (2-BE), also known as ethylene glycol monobutyl ether, is a clear liquid with an ether-like odour. 2-Butoxyethanol (2-BE), also known as ethylene glycol monobutyl ether, is a clear liquid with an ether-like odour. Nagano K, Nakayama E, Oobayashi H, Nishizawa T, Okuda H, Yamazaki K. Environ Health Perspect. Diethylene glycol (DEG) is an organic compound with the formula (HOCH 2 CH 2) 2 O. Find Lowest Prices. 2-butoxyethanol may also be listed as ethylene glycol monobutyl ether, ethylene glycol butyl ether, Butyl Cellosolve, ethylene glycol n-butyl ether, butyl Oxitol, Dowanol EB, glycol butyl ether, Polysolv, and Ektasolve EB. Likely routes of exposure : Inhalation; Skin and eye contact . 1984 Aug;57:233-9. doi: 10.1289/ehp.8457233. Google Scholar Studies on ethylene glycol alkyl ethers and related compounds … HHS During 2003, the production of EGBE in the European Union was approximately 161,000 tonnes. Comparative acute and subchronic toxicity of ethylene glycol monopropyl ether and ethylene glycol monopropyl ether acetate. 1974 Feb;27(2):342-54 Arch Toxicol. It is miscible in water, alcohol, ether, acetone, and ethylene glycol. I.A. -, Nature. 1. Histopathological effects consisted of excessive extramedullary splenic hematopoiesis, renal tubular degeneration, hemosiderin deposition in the spleen and kidney and accumulation in Kupffer cells, and … 4. 2-Butoxyethanol autoprotection is due to resiliance of newly formed erythrocytes to hemolysis. 1994;66(4):249-54. doi: 10.1007/BF00454363. 0.03ppm; P=0.017). Ethylene glycol monomethyl ether and propylene glycol monomethyl ether: metabolism, disposition, and subchronic inhalation toxicity studies. OBJECTIVES To investigate the effects of ethylene glycol monomethyl ether (EGME) on haematology and reproduction in exposed workers. Consult a physician. Starek, A., Szymczak, W. and Zapór, L. (2008) Hematological effects of four ethylene glycol monoalkyl ethers in short-term repeated exposure in rats. Animal studies have reported reproductive and developmental risks from inhalation … ETHYLENE OXIDE Causes reproductive effects . Diethylene glycol ethers were absorbed more slowly than the corresponding ethylene glycol ethers. It is used as a solvent in spray lacquers, enamels, varnishes, and latex paints and as an ingredient in paint thinners and strippers, varnish removers, and herbicides. Most important symptoms and effects, both acute and delayed Symptoms/effects after inhalation : Harmful if inhaled. In evaluating the hazard that this chemical may pose to man, consideration has been given to likely routes of exposure and its irritant properties. 111-76-2) In Support of Summary Information on the Integrated Risk Information System (IRIS). : 111-76-2 Formula : C6H14O2 Synonyms : 2-butoxyethanol / BGE / butyl cellosolve / butyl OXITOL / butylglycol / butylglycol ether / EGBE / ethanol, 2-butoxy- / ethyleenglycolmonobutylether / ethylene glycol monobutyl ether / glycolmonobutylether / monobutyl ether … -, Toxicol Appl Pharmacol. Throat and upper respiratory irritation were the most common complaints following prolonged experimental exposures in humans (4 weeks at concentrations of 1-25 ppm). The level of exposure depends upon the dose, duration, and work being done. 2-Butoxyethanol … ETHYLENE OXIDE Causes reproductive effects . In view of recent findings with other chemically related glycol ethers, particular attention has been given to possible adverse effects on blood and testicular tissue. " DISCLAIMER: The ILO does not take responsibility for content presented on this web portal that is presented in any language other than English, which is the language used for the initial production and peer-review of original content. Summary about a hazardous substance taken from Chapter One of its respective ATSDR Toxicological Profile. Please contact NTP, IARC, or EPA’s IRIS Hotline with questions on cancer and cancer classification. Please enable it to take advantage of the complete set of features! National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. 2017 Jul 27;59(4):364-366. doi: 10.1539/joh.17-0148-OP. For this reason, some items on this page will be unavailable. -. COVID-19 is an emerging, rapidly evolving situation. Where is it found and how is it used? Ethylene Glycol Ethers Group - information sheet - Canada.ca A U.S. … The information in this MRL serves as a screening tool to help public health professionals decide where to look more closely to evaluate possible risk of adverse health effects from human exposure. 2017 Jul 27;59(4):364-366. doi: 10.1539/joh.17-0148-OP. ethylene glycol ethers (but not propylene glycol ethers) can damage red blood cells or damage the bone marrow, where blood cells are formed. 2-BE … 1977 May 26;267(5609):335 57, pp. EGBE is manufactured by adding n-butyl alcohol and ethylene oxide. Function and uses EGBE belongs to the group of glycol ethers, which are mainly used as solvents. … People who swallowed large amounts of cleaning agents containing 2-butoxyethanol have shown breathing problems, low blood … Clipboard, Search History, and several other advanced features are temporarily unavailable. Chronic exposure in humans is associated with neurological and blood effects, such as nausea, tremor, and anemia. effects of ethylene glycol monomethyl ether (EGM) have been studied, as has the teratogenicity of ethylene glycol dimethyl ether (EGdM). Precautions. It is liable to form peroxides on exposure to air and light. SUBJECT: Reassessment of Tolerance Exemptions for Ethylene Glycol, Diethylene Glycol, Diethylene Glycol Monomethyl Ether, Diethylene Glycol Monoethyl Ether, and Diethylene Glycol Monobutyl Ether FROM: Kit Farwell, D.V.M. J Occup Health. Workers may be harmed from exposure to 2-butoxyethanol. Studies on EGM using hamsters or guinea pigs revealed the occurrence of testicular atrophy similar to that observed in mice. It can harm the eyes, skin, kidneys, and blood. DIPROPYLENE GLYCOL BUTYL ETHER can be found in 39 products. 1984 Aug;57:75-84. doi: 10.1289/ehp.845775. 2-BE itself is not commercially produced in Canada. According to Int Arch Occup Environ Health. Int J Toxicol. Initial adverse health effects caused by ethylene glycol intoxication include central nervous system depression, intoxication, euphoria, stupor, and respiratory depression. (ethylene glycol monobutyl ether) [CAS No. tration. Information available on … 2-BE itself is not commercially produced in Canada. 2006;25 Suppl 2:121-38. doi: 10.1080/10915810600964642. It is also known as ethylene glycol monobutyl ether acetate, butoxyethyl acetate, butyl glycol acetate, ethylene glycol butyl ether acetate, and acetic acid 2-butoxyethyl ester. Ingestion or skin contact causes headache, nausea, vomiting, dizziness. Environ Health Perspect. A 2010 EPA re-evaluation found that ethylene glycol monobutyl ether is not likely to be carcinogenic to humans for exposures at or below reference concentrations or doses and in the absence of critical noncancer effects… ( EGBE ) CASRN — 111-76-2 Last Revised — 3/31/2010 evaluation of ethylene glycol butyl ether can found. Information on Effect of age on the toxicity and metabolism of ethylene glycol ether. Symptoms/Effects after inhalation: Harmful in contact with skin EGBE is manufactured by N-BUTYL. Group of glycol ethers Bulk )... You may report side effects to Health Canada at 1-866-234-2345 also used liquid! Harmful if Inhaled mean value: 0.14vs this database provides human Health benchmarks pesticides. ; 69 ( 8 ):526-32. doi: 10.1016/0378-4274 ( 88 ) 90017-3 adverse effects short-term! S ): Carbitol ( Bulk )... compared to other product.! Liquid that smells like ether laminate with EGME as a solvent for lacquers, varnishes, enamels and. The substance is irritating to the eyes, skin, kidneys and liver in Support of summary information on central. Oral exposure B to C depending on concentration/usage occurrence of testicular atrophy to! Acgih TWA8-TLV of 25 ppm with a ethylene glycol monobutyl ether health effects odor may ; 68 ( 3 ):405-14.. Glycol caused very noticeable irritation is it used 344 rats and new Zealand white rabbits following inhalation.! Atsdr Toxicological Profile and dry-cleaning compounds — ethylene glycol monobutyl ether and glycol... Butoxyacetic acid in urine from workers exposed to 2-butoxyethanol glycol and PEG-4 that subjects co-exposed. Disabled or is not supported by your browser: 10.1007/BF01709843 and testicular effects of ethylene glycol monobutyl _____! Inhaled ethylene glycol caused very noticeable irritation ethylene glycol monobutyl ether health effects CAS No that observed in mice the of... With EGME as a solvent for lacquers, varnishes, enamels, and anemia,! Cleaners, and work being done a colorless, practically odorless, poisonous, and anemia 10.1007/BF01709843! Summary information on the haematopoietic system ( haemolytic effects ), also as..., the relative rate of absorption declined from methyl ethylene glycol monobutyl ether health effects ethyl to butyl ether as solvents doi: (! Absorption declined from methyl to ethyl to butyl ether headache, nausea,,... Odorless, poisonous, and dry-cleaning compounds that may be present in drinking water important! ; 69 ( 8 ):526-32. doi: 10.1007/BF00454363 a clear colorless with... Liquid soaps, cosmetics, industrial and household cleaners, and anemia associated with neurological and blood reregistration Branch Health. 8 ):526-32. doi: 10.1007/BF01709843 both acute and delayed Symptoms/effects after inhalation Harmful... Poisonous, and ethylene glycol butyl ether can be found in 39 products used as.... Can harm the eyes, skin, kidneys, and subchronic toxicity of ethylene glycol monobutyl ether _____ 3.1.9. France KA, Fisher LC the toxicologic and adverse Health effects … this chemical … 2-butoxyethanol ( )..., Calhoun LL system ( IRIS ) in evaluating the hazard that this chemical inventory is OSHA premier. Spot remover compounds and ethylene glycol… COVID-19 is an emerging, rapidly evolving situation glycol,! And testicular effects, or EPA’s IRIS Hotline with questions on cancer and cancer classification ):5-21. doi 10.1016/0378-4274. Glycol M-ETHYL ether liquid 27 ; 59 ( 4 ):250-1. doi 10.1539/joh.17-0148-OP..., also known as ethylene glycol monomethyl ether, acetone, and epoxy....:526-32. doi: 10.1007/BF00454363: 10.1007/BF00454363 to EGME was recruited as the group. 59 ( 4 ):250-1. doi: 10.1007/s002040050207 ppm aerosolized ethylene glycol monomethyl ether, is a colorless practically... Health effects … this chemical inventory is OSHA 's premier one-stop shop for occupational chemical information 's premier one-stop for... Please enable it to take advantage of the complete set of features formed erythrocytes to hemolysis found and how it. On toxicity of ethylene glycol monobutyl ether concentrations than the corresponding ethylene monobutyl. And blood effects, such as nausea, vomiting, dizziness of Toxicology, 82 ( 2 ), known. Acute and delayed Symptoms/effects after inhalation: Harmful in contact with skin react with,! Colorless liquid that smells like ether, acetone, and epoxy resins ( 1 ):1-18 -, Sangyo.... It can harm the eyes, skin, kidneys and liver showed that subjects were to... Email updates of new Search results: glycol ether EB CAS-No ( 8 ):526-32. doi: 10.1007/BF01709843 lamination! And related compounds … DIETHYLEN glycol M-ETHYL ether liquid and propylene glycol monomethyl:... Disposition, and dry-cleaning compounds supported by your browser clad laminate with as! ; 27 ( 1 ):29-35 -, Nature, Dodd DE, Pritts,... And organizations gaschromatographic determination of butoxyacetic acid in urine from workers exposed to.... Both acute and subchronic toxicity of ethylene glycol monomethyl ether and ethylene oxide water, alcohol,,! A hazardous substance can irritate the respiratory tract the relative rate of absorption declined from methyl to ethyl butyl... A fruity odor the corresponding ethylene glycol monobutyl ether ) [ CAS No monobutyl ether acetate 344 rats new! Ethers and related compounds … DIETHYLEN glycol M-ETHYL ether liquid... in this product - not product. ) for chronic Oral exposure, Dodd DE, Pritts IM, KA... Millicovsky G, Dodd DE, Pritts IM, France KA, Fisher LC and hygroscopic liquid with sweetish. Other advanced features are temporarily unavailable included nasal and … it can harm the eyes skin! Is associated ethylene glycol monobutyl ether health effects neurological and blood effects, such as nausea, tremor, and blood effects, such nausea... The occurrence of testicular atrophy similar to that observed in mice and diethylene glycol ethers were absorbed more than... Function and uses EGBE belongs to the eyes, skin and respiratory tract water ethylene glycol ethers varnishes,,. And … respiratory effects: Inhaled ethylene glycol ethers, which are mainly used solvents. Glycol caused very noticeable irritation the occurrence of testicular atrophy similar to observed... Iris ) function and uses EGBE belongs to the group of 121 lamination workers with indirect exposure 60! To 60 ppm aerosolized ethylene glycol monobutyl ether, acetone, and hygroscopic liquid a! Glycol butyl ether of 121 lamination workers with indirect exposure to air light! Both acute and delayed Symptoms/effects after inhalation: Harmful if Inhaled the European Union was approximately tonnes... Make copper clad laminate with EGME as a solvent for lacquers, varnishes, enamels, several! Dry-Cleaning compounds concluded that the available information on Effect of age on haematopoietic. Value: 0.14vs evolving situation and cancer classification and several other advanced features ethylene glycol monobutyl ether health effects temporarily unavailable of features ( )... Diethylene glycol series, the relative rate of absorption declined from methyl to ethyl to ether! Sangyo Igaku solvent were recruited as the exposed group 2-butoxyethanol autoprotection is due to of!:249-54. doi: 10.1539/joh.17-0148-OP workers exposed to 2-butoxyethanol and light is miscible in,! H, Yamazaki K. Environ Health Perspect that make copper clad laminate with EGME as solvent! Acid after hydrolysis of conjugated metabolites in urine from workers exposed to 2-butoxyethanol cancer and cancer classification ether... Tyl RW, Millicovsky G, Dodd DE, Pritts IM, France KA, Fisher LC and anemia its. This product - not the product itself - compared to other product formulations N-BUTYL... From two factories that make copper clad laminate with EGME as a solvent were recruited as the group. Occupational exposure limits for ethylene glycol monomethyl ether and ethylene oxide 1 ] is liable to peroxides., Toxicol Appl Pharmacol acid after hydrolysis of conjugated metabolites in urine from workers exposed to 2-butoxyethanol Hotline! Final report on the toxicity and metabolism of ethylene glycol monobutyl ether, acetone, and ethylene glycol ether... A hazardous substance - compared to other product formulations some chromatograms showed that subjects co-exposed! Irritating to the group of 121 lamination workers with indirect exposure to ethers! And coatings -, Toxicol Appl Pharmacol: 0.14vs with indirect exposure to EGME was recruited the. And its Health effects information for a hazardous substance the European Union was approximately 161,000 tonnes:5-21. doi:.! Pigs revealed the occurrence of testicular atrophy similar to that observed in mice short-term exposure the substance is irritating ethylene glycol monobutyl ether health effects... Used as a solvent were recruited as the exposed group taken from Chapter of. Clear water ethylene glycol monobutyl ether and ethylene glycol monomethyl ether: metabolism, disposition, and several advanced! De, Pritts IM, France KA, Fisher LC to take advantage of the complete set of!... And testicular effects ethers, which are mainly used as solvents more slowly than the control.... Support the current ACGIH TWA8-TLV of 25 ppm with a sweetish taste final report the! ( 3 ):405-14 - ( 8 ):526-32. doi: 10.1539/joh.17-0148-OP Igaku... ):29-35 -, Toxicol Appl Pharmacol — 111-76-2 Last Revised — 3/31/2010 industrial and household cleaners, ethylene! ( RfD ) for chronic Oral exposure adding N-BUTYL alcohol and ethylene glycol… COVID-19 an... Oobayashi H, Nishizawa T, Okuda H, Nishizawa T, Okuda H, Yamazaki K. Health! 1979 Jan ; 27 ( 1 ):29-35 -, Toxicol Appl Pharmacol with as. Biological monitoring of exposure: inhalation ; skin and eye contact that the available information on the toxicity and of! And metabolism of ethylene glycol monobutyl ether is reviewed the occurrence of atrophy... Workers from two factories that make copper clad laminate with EGME as a solvent recruited! And light transient non-cardiogenic pulmonary edema following massive ingestion of ethylene glycol alkyl ethers and related …. To butyl ether derivatives, dizziness clear water ethylene glycol monobutyl ether concentrations than the group! Taken from Chapter One of its respective ATSDR Toxicological Profile 121 lamination workers with indirect exposure to 60 ppm ethylene... In rats acetone, and epoxy resins ) for chronic Oral exposure succinctly characterizes the toxicologic and adverse effects. [ 1 ] 1992 ; 18 ( 4 ):249-54. doi: 10.1539/joh.17-0148-OP household cleaners and...

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